Heart of the Mekong Delta
This city is the centre of trade in the Mekong Delta, so it's a very large city - not on the scale of HCMC but still big. This shows in terms of the height of the buildings and the fact that all the things that you need to buy are to be found within a one block radius of where you are staying.
Can Tho is neither an attractive nor unattractive city; it is there and it functions, that is it's purpose and it does it well.
From Can Tho you are able to explore the Mekong Delta, which is a vast area of rice paddies, vegetable gardens, and the usual things that you find in regional areas.